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Development and Validation of HPTLC Methods for Estimation of Trimebutine Maleate in Pharmaceutical FormulationBy R.P. Bhole, Deepa Jadhav, S.B. Wankhede, Y.B. Zambare
Abstract: A simple and rapid high-performance thin-layer chromatographic (HPTLC) method was developed and validated for quantitative determination of trimebutine maleate in single dose formulation. Trimebutine maleate was chromatographed on silica gel 60 F 254 TLC plate using methanol–toluene (8:2 v/v) as mobile phase. The plates were developed to a distance of 8 cm at ambient temperature. Trimebutine maleate was quantified by densitometric analysis at 271 nm. The method was found to …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 1, 2017 · pp. 17–22 Read article →