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A Brief Review on Inflammatory Mediators and Drug Therapy for Rheumatoid ArthritisBy Puja Kumari Rai, Vimukta Sharma, Jayanti Mukharjee, Vipin V Dhote
Abstract: Rheumatoid arthritis (RA) is an autoimmune disease which is characterized by inflammation of the joints and destruction of cartilage and bone. The disease pathology is complex which involves the infiltration and activation of various populations of immune cells along with the release of destructive inflammatory mediators into the synovium of affected joints. Several inflammatory mediators are involved in just like IL-1, IL-6, IL-8, IL-17, IL-18 and tumour necrosis factor-alfa. Treatment …
Published in Trends in Drug Delivery · Vol. 6, Issue 2, 2019 · pp. 1–4 Read article →