2 publications
-
Published Subscription
Formulation and Development of Gastroretentive Hydrogels of GlipizideBy Vasanth Samaga, S.B. Puranik
Abstract: The aim of the present study was to develop a pH sensitive gastroretentive drug delivery system for an antidiabetic drug glipizide, based on gas formation technique using 32-factorial design, in order to prolong the gastric residence time and increase the overall bioavailability of the dosage form, since the absorption is erratic in diabetic patients. The system consists of the drug, glycol chitosan (5% w/w) and aqueous PVA solution (10% w/w) …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 4, Issue 1, 2017 · pp. 1–7 Read article →
-
Published Subscription
Formulation and Development of pH Sensitive Drug Delivery Systems for Antihyperglycemic DrugsBy Vasanth Samaga, S. B. Puranik
Abstract: The aim of the present study was to develop a pH sensitive gastroretentive drug delivery system for an anti-diabetic drug pioglitazone HCl based on gas formation technique using 32 factorial design, in order to prolong the gastric residence time and increase the overall bioavailability of the dosage form, since the absorption is erratic in diabetic patients. The system consists of the drug loaded pellets which is coated with two different …
Published in Trends in Drug Delivery · Vol. 4, Issue 1, 2017 · pp. 8–17 Read article →