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Published Subscription Original Research
Engineering of PEG-b-PCL/Pluronic F127 Polymeric Composite Micelles for Controlled Co-Delivery of Docetaxel and Curcumin in Prostate Cancer TherapyBy Mahesh M. Nosenoor, Sunil Kumar Singh, Anubi Badhani, Raj K. Keservani, Sujit Appasaheb Jadhav, Sachin Nathu Kapse, Saurabh Das Vaishnaw
Abstract: Polymeric composite nanocarriers made from amphiphilic block copolymers are popular for their customisable architecture, self-assembly behaviour, and drug release control. A PEG-b-PCL/Pluronic F127 micellar composite was developed and tested as a multifunctional nanocarrier for docetaxel and curcumin administration.The amphiphilic block copolymers Pluronic® F127 and PEG-b-PCL were employed to generate polymeric micelles using solvent evaporation-assisted self-assembly. The optimised polymer composite showed good colloidal stability and uniform size distribution with a zeta …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 Read article →