1 publication

• Published Subscription 5 Sep 2016

  CRISPR-Cas System: Next Generation Genome Editing Tool

  By Monika ., Rahul Kumar Meena, Leela Wati

  Abstract: CRISPR-Cas system provides sequence specific adaptive immunity against phages and mobile genetic elements. Resistance is acquired following phage infection or plasmid uptake when short specific sequence is added into CRSIPR array. This complex guides cRNA to target complementary DNA fragments and target its degradation. CRISPR array is then transcribed and processed into cRNA which forms complex with cas protein. The ability of CRISPR-Cas system to induce site specific DNA breaks …

  Published in Research and Reviews : A Journal of Biotechnology · Vol. 6, Issue 2, 2016 · pp. 10–16 Read article →