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Optimization of Mobile Phase and Stability—Indicating HPTLC Method for the Determination of Prasugrel Hydrochloride in Pharmaceutical Dosage FormBy Richa I Champaneria, Pratik Tailor, Ashish D Mishra, Shailesh A Shah
Abstract: A simple and sensitive high-performance thin layer chromatographic method was developed and validated for Prasugrel hydrochloride. It was spotted on silica gel 60F254 TLC plates, developed using toluene:methanol (9.9:0.1, v/v) as mobile phase and scanned at 258 nm using a Camag TLC Scanner IV. The Rf value of Prasugrel hydrochloride were found to be 0.53±0.03. It was found to be linear in the concentration range of 300–1500 ng/band. The limit …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 2, 2018 · pp. 7–12 Read article →