1 publication

• Published Subscription 7 May 2017

  Modified Nucleosides “(ProTide)” as Potential Anti-HCV Therapeutics

  By N. A Elsharif, O. Dakeel

  Abstract: Hepatitis C virus (HCV) is among the most common causes of cirrhosis and chronic liver disease worldwide. As a result, many researchers are interested in designing and synthesis of a clinical treatment for HCV. Nucleoside monophosphates and monophosphonates play such an important role for treatments of incurable diseases such as hepatitis. For example, 2'-C-methyladenosine and 2'-C-methyl guanosine have shown activities against HCV in the replicon assay as well as against …

  Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 1, 2017 · pp. 32–39 Read article →