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Formulation and Evaluation of Transungual Drug Delivery of Fluconazole Using Permeation Enhancers Screened by Hydration of Nail PlateBy Arun Raj R., Nithin Kurian
Abstract: The objective of the work was to formulate nail lacquer containing fluconazole an antifungual drug for the treatment of onychomycosis. Onychomycosis, a common fungal nail infection affects the people. Topical and ungual therapy is limited because of the poor permeation of the drug through nail plate. Film base was prepared using varying concentration of cellulose acetate and ethyl cellulose as polymers. The permeation enhancers were screened by nail plate hydration. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 3, 2017 · pp. 32–45 Read article →