2 publications

• Published Subscription 29 Apr 2019

  Over Expression of Genes at Long Arm of 21 Chromosome in Case of Down Syndrome

  By Nimisha Kumari

  Abstract: Down Syndrome (DS) is a genetic disorder which is caused due to trisomy at chromosome 21 or gene dosage imbalance. DS leads to mental retardation in humans. It is a multisystem disorder as it affects several systems of our body like cardiovascular, respiratory, gastrointestinal, neurological, hematopoietic and musculoskeletal system. The principal cause of DS is unknown yet. Some factors are responsible for DS. like reproduction at advanced maternal age, folic …

  Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 2, 2015 · pp. 27–34 Read article →

• Published Subscription 4 Apr 2019

  Down’s Syndrome (DS): A Genetic Disorder

  By Nimisha Kumari

  Abstract: Down’s syndrome (DS) is a chromosomal disorder which occurs due to an error in cell division subsequently leading to an extra 21st chromosome. DS or trisomy 21 is a condition where an individual has 47 chromosomes in each cell instead of 46. It is a multisystem disorder as it affects more than one system of our body. As a consequence, impairments in both cognitive ability and physical growth take place …

  Published in Research and Reviews : A Journal of Immunology · Vol. 5, Issue 2, 2015 · pp. 21–26 Read article →