2 publications

• Published Subscription 22 Apr 2013

  Anti-nociceptive Potential of Scurrula parasitica: An Unexploited Parasitic Plant

  By Nilesh Mahajan, Parag Joshi, Manish Kondawar, K. L. Senthil Kumar, V. Vaidhyalingam

  Abstract: Scurrula parasitica (Loranthaceae) is an herbaceous growing shrub parasitic on Dendrophthoe falcata (Loranthaceae) which is itself parasitic on Mangifera indica (Anacardiaceae). Scurrula parasitica is distributed throughout the western ghat region of Maharashtra, some parts of Uttar Karnataka and Tamil Nadu. Genus Scurrula comprising of around 91 species, however, only S. ferruginea, S. atropurpurea, S. fusca have been investigated systematically. No such pharmacological and phytochemical data are available on the plant …

  Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 1, 2013 · pp. 4–8 Read article →

• Published Subscription 24 Jan 2011

  Protease activated receptor-2 as an imperative target in nociceptive responses: A minireview

  By Nilesh Mahajan

  Abstract: PARs (protease-activated receptors) are a family of seven-transmembrane G-protein coupled receptor for proteases from circulation, inflammatory cells and endothelial tissues. To date, four members of PAR family have been cloned, namely PAR1 to PAR4. This minireview focuses on role of PAR2 receptor in inflammatory and nociceptive processes. Numerous studies documented for activation of PAR2 receptors through several proteases suggests its role in pain and inflammation. However, mechanism of PAR2 underlying …

  Published in Research and Reviews: A Journal of Pharmacology · Vol. 1, Issue 1, 2011 · pp. 8–13 Read article →