2 publications

• Published Subscription 15 Jul 2019

  Induction of G1 Phase Cell Cycle Arrest and Apoptosis in Breast Cancer MCF-7 Cells by Sulphonamide Derivative CID-6861424

  By Sumit Kumar Gautam, Afreen Inam, Amir Azam, N. Mondal

  Abstract: Breast cancer is most frequently detected and leading cause of cancer death in women worldwide. 80% of the breast cancer are estrogen receptor positive and the presently available drugs are ineffective either due to intrinsic resistance or due to acquired resistance. Sulfonamide compounds are a class of compounds showing activities like, antibacterial, antiviral including antitumor. In the present study we have investigated the anti-cancerous activity of sulfonamide derivative CID-6861424 on …

  Published in Research and Reviews: A Journal of Toxicology · Vol. 9, Issue 2, 2019 · pp. 1–17 Read article →

• Published Subscription 12 Apr 2019

  Tamoxifen: Role in Breast Cancer Treatment

  By N. Mondal, S. Ali

  Abstract: Breast cancer is one of the most common cancers among women worldwide. In the last two decades, there have been various therapies proposed for the treatment and prevention of breast cancer. One of them is targeted hormonal therapy (THT) for the estrogen and its receptor in breast cancer. The synthetic selective estrogen receptor modulator, tamoxifen is in the use for treating, estrogen receptor-positive breast cancer from the last 30 years. …

  Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 5, Issue 1, 2016 · pp. 1–19 Read article →