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Flavonoids Attenuate Airway Mucin Expression, Production and Secretion Induced by Various InducersBy Md. Asaduzzaman Sikder, Md. Zainul Abedin, Md. Abu Zubair, Hyun Jae Lee, Choong Jae Lee
Abstract: Muco-obstructive respiratory disease is caused by changing normal biophysical properties of mucus including alteration of mucin concentration, ion composition and airway surface hydration. Flavonoids are one type of polyphenols which regulate mucin gene expression and consequently inhibit mucus secretion. Thus, this review aimed to discuss the effects of different flavonoids on regulation of various airways mucin gene expression and inhibition of the production of a major airway mucin core protein …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 2, 2019 · pp. 1–13 Read article →