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Flavonoids Regulate Airway MUC5AC Mucin Expression through Modulation of Multiple Signalling PathwaysBy Md. Asaduzzaman Sikder, Md. Zainul Abedin, Md. Abu Zubair, Mohammod Johirul Islam, Choong Jae Lee, Hyun Jae Lee
Abstract: Airway mucus is a component of pulmonary innate immune function and plays very important role in defense against invading pathogenic microbes, chemicals and particles. The protective function of airway mucus is attributed to the viscoelasticity of mucins. Mucins are large glycoproteins play important role in cell–cell adhesion, airways protection, Nuclear-factor kappa B signalling, epidermal growth factor receptor signalling. Eleven mucin genes (among twenty identified mucin genes) have been expressed at …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 3, 2017 · pp. 21–33 Read article →