1 publication

• Published Subscription 8 Nov 2023

  Current Trends in Crossing the Blood–Brain Barrier: A Review

  By Chenna M Shalini, Komati Manasa, Zafar Khan, Manga Meghana, Rama Rao T

  Abstract: The blood-brain barrier (BBB) is a protective barrier that protects the central nervous system (CNS) from toxins and pathogens in the blood. However, the existence of BBB challenges therapy for CNS diseases and disorders as most pharmaceuticals (drugs) are restricted to enter brain. The review article focuses on the approaches involved to cross BBB with various advanced technology such as nanoparticles, intraventricular injection, chemical modifications, virus mediated distribution, exosome mediated …

  Published in Trends in Drug Delivery · Vol. 10, Issue 2, 2023 · pp. 25–38 Read article →