2 publications

• Published Subscription 10 Apr 2019

  In Vivo and In Vitro Antioxidative Efficacy of Naringenin on Cadmium -Induced Toxicity in Rats

  By S. Milton Prabu, J. Renugadevi, K. Shagirtha

  Abstract: The aim of the study was to investigate the in vivo circulating antioxidants level such as vitamin C, vitamin E and GSH in Cadmium (Cd) induced toxic rats and the protective efficacy of naringenin via in vitro free radical scavenging assays. In this investigation cadmium chloride (5 mg/kg body weight (b.w) was administered orally (p.o) for 28 days to induce toxicity. Naringenin was pre-administered orally (50 mg/kg body weight) for …

  Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 3, 2013 · pp. 9–16 Read article →

• Published Subscription 9 Apr 2019

  Cadmium and Apoptosis: A Molecular Approach

  By S. Milton Prabu, K. Shagirtha

  Abstract: Apoptosis, also known as programmed cell death is a highly regulated and fundamental process found in all multicellular organisms. It is not only implicated in regulatory mechanisms of cells, but has been attributed to a number of diseases, like inflammation, malignancy, autoimmunity and neuro-degeneration. A variability of pollutants can persuade apoptosis. Oncogenic transition metals like cadmium, promote apoptosis alongside DNA base modifications, strand breaks and rearrangements. Generation of reactive oxygen …

  Published in Research and Reviews: A Journal of Toxicology · Vol. 6, Issue 1, 2016 · pp. 8–17 Read article →