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Formulation And Evaluation of Domperidone Medicated Jelly Using Solvent Deposition Method For Solubility EnhancementBy Arun Raj R., Jibcy Feba Rachel John, Jyoti Harindran
Abstract: Objective: The purpose of this study is to develop and characterize medicated jelly of Domperidone. Domperidone is associated with poor aqueous solubility and dissolution rate and thus exhibit a poor bioavailability. Solvent deposition is a promising method to improve the solubility of poor water soluble drugs.Methods: Solvent depositions were prepared for optimization and evaluated for percentage drug content, invitro dissolution, solubility analysis. Optimization of Domperidone solvent deposition was done using …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 4, Issue 2, 2017 · pp. 40–53 Read article →