5 publications
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In Vitro Efficacy of Some Medicinal Plant Extracts against Aspergillus Niger: A Disease Causing Plant FungusBy JENIFER SOLOMON RAJAN, John Bastin T. M. M., Kezia Laveena D., Singh S. J. S, Priya S
Abstract: Medicinal plants have been used in the prevention, treatment, and cure disorders and diseases in ancient times and they provide abundant resources of antimicrobial compounds, has been used for centuries to inhibit the microbial growth. Diseases of medicinal plants were caused by the pathogenic microbes: especially fungi are common throughout the world. Microbial diseases of plants cause malfunctions such as disturb normal functions by degrading enzymes, toxin, and growth substances, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 1, Issue 2, 2014 · pp. 11–17 Read article →
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Studies on the Biodegradation of Hydrocarbons using Pseudomonas aeruginosa and Aspergillus nigerBy JENIFER SOLOMON RAJAN, J. Shanofer, S. Priya, J. Krishnakumar
Abstract: Biodegradation or biotic degradation or biotic decomposition is the chemical dissolution of material by bacteria or other biological means. The term is often used in relation to ecology, waste management, biomedicine, and the natural environment (bioremediation) and is now commonly associated with environmentally friendly products that are capable of decomposing back into natural elements. Organic material can be degraded aerobically with oxygen, or an aerobically, without oxygen. A term related …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 2, Issue 2, 2015 · pp. 11–13 Read article →
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Single Nucleotide Polymorphism in CYP17 and CYP19 in Breast CancerBy JENIFER SOLOMON RAJAN, Laveena D. K., Singh S. J. S
Abstract: A single T > C change at the 5’ promoter region of the CYP17 and CYP19 genes are reported to be associated with increased risk of breast cancer. This study evaluates the influence of genetic polymorphism of CYP17 and CYP19 on breast cancer susceptibility. Ten patients with histopathologically confirmed breast cancer and 30 age-matched controls were included in study. A polymerase chain reaction – single nucleotide polymorphism (PCR-SSCP) method was …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 2, 2014 · pp. 8–11 Read article →
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Antibacterial Activity of Leaf and Flower Extract of Lablab purpureus against Clinical Isolates of Staphylococcus aureusBy JENIFER SOLOMON RAJAN, Jenifer S.
Abstract: The present study was undertaken to determine inhibitory activity of leaf and flower extracts of Lablab purpureus against clinical isolates of Staphylococcus aureus. Agar well diffusion assay was performed to determine antibacterial activity. Among extracts, the flower extract has shown marked inhibition of S. aureus isolates. It can be concluded that the leaf and flower extracts possess inhibitory components. The bioactive components present in the plant are to be separated …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 2, 2014 · pp. 5–7 Read article →
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Antibacterial Activity and Preliminary Phytochemical Screening of the Extracts of the Bark of Moringa oleiferaBy JENIFER SOLOMON RAJAN, Priya S
Abstract: Ethyl acetate, acetone, methanol and aqueous extracts of the bark Moringa oleifera were screened against the enteric pathogens isolates namely, Esherichia coli, Shigella sonnei and Salmonella enteritis. All the extracts other than aqueous extract showed antimicrobial activity with the methanol extract having the percentage of activity. Preliminary phytochemical screening revealed the presence of and tannins in the methanol extract. Keywords: Moringa oleifera, bark, antimicrobial activity, flavones, tannins
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 1, Issue 2, 2014 · pp. 1–4 Read article →