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Design and Evaluation of Itraconazole NiosomesBy Panner Selvam R, Jaidul Islam, Vineeth Chandy
Abstract: The present study was undertaken with an aim to fabricate and characterize and evaluate niosomes of Itraconazole, where the drug is released in a sustained manner for a period of 12 hours. Itraconazole is Class-2 drug having low solubility and have short half-life between 3–4 hours. Due to high first pass metabolism, the drug is rapidly excreted from the body indicating the need of sustained release delivery. To overcome these …
Published in Trends in Drug Delivery · Vol. 9, Issue 1, 2022 · pp. 62–68 Read article →