2 publications
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Published Subscription
Development and Validation of a Gradient RP-HPLC Method for Quantitative Determination of Potential Manufacturing Impurities in New Drug Apronalide and Pharmaceutical FormulationsBy Ritesh Mishra, Hitesh Malvia, M. Asif Khan
Abstract: Three impurities in apronalide drug substance were detected and quantified using a simple isocratic reverse phase HPLC method. The chromatographic separation was achieved on a Thermo Hypersil gold-CN, 100 A0 5 µm, and 250X4.6 mm using a mobile phase consisting of phosphate buffer (pH-4.6) - Methanol with UV detection at 210 nm and flow rate of 0.8 ml/min. The column temperature was maintained at 250C throughout the analysis. This method …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 1, Issue 1, 2014 · pp. 1–10 Read article →
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Published Subscription
Development and Validation of a High Performance Liquid Chromatographic Method for Related Substances of Raloxifene Hydrochloride in Bulk and Pharmaceutical FormulationsBy Ritesh Mishra, Satish Matkar, Hitesh Malvia, M.Asif Khan
Abstract: The development and validation of reversed phase liquid chromatographic method for the determination of the related substances of Raloxifene Hydrochloride (RLH) in bulk and pharmaceutical formulation is describe. This method is simple isocratic for separation of Raloxifene Hydrochloride and related substances from each other in a thirty minutes run time. To the best of our knowledge, no method described previously in the literature has demonstrated resolution of RLH from this …
Published in Trends in Drug Delivery · Vol. 1, Issue 1, 2014 · pp. 16–23 Read article →