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• Published Subscription 18 Mar 2019

  Molecular Interaction and Simulation Studies of Inhibitors for Endothelin-1 Receptors

  By P. Shanmughavel, Grace Ratna Roy

  Abstract: High altitude cerebral edema (HACE) is a life threatening severe form of acute mountain sickness (AMS) which causes headache, unbalanced gait, behavioral changes, and altered mental status. It also carries features like hallucinations or coma, as well as a variety of neurological deficits. Prevention of edema fluid formation with minimal side effects remains to be discovered. Endothelin-1 receptors were found to be involved in the pathogenesis of HACE. Due to …

  Published in Research & Reviews: A Journal of Bioinformatics · Vol. 2, Issue 3, 2015 · pp. 15–26 Read article →