2 publications

• Published Subscription 23 Apr 2014

  Patterns of Antihypertensive Drug Utilization in a West Indies University Teaching Hospital

  By Gopalakrishna Pillai, Emily Esposito, Seetharaman Hariharan, Claudette Gomez

  Abstract: Objective of this study was to determine the prescribing patterns of antihypertensive medications in specialty outpatient clinics in a tertiary care hospital of a Caribbean developing country. A retrospective prescription-based survey was conducted in the renal and cardiac outpatient clinics during the period September to December 2006. Data recorded included demographic data, antihypertensive and other drugs prescribed, duration of prescription, adverse drug reactions and side effects. A total of 285 …

  Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 1, 2014 · pp. 26–34 Read article →

• Published Subscription 23 Apr 2014

  Enhanced Iron Removal in Experimental Iron Overload by Nanoniosomes of Desferrioxamine

  By Gopalakrishna Pillai, Bhagwandin Cindy

  Abstract: This preliminary study explores the feasibility of employing nanocapsules prepared from nonionic surfactant vesicles (niosomes) as a carrier for an iron-chelating agent, Desferrioxamine (DFO, Desferal), to enhance iron excretion from the body. The methodology consisted of creating an iron overload model in an experimental animal followed by measurement of iron excretion pattern in the urine by atomic absorption spectrophotometry. Niosomes were prepared with span 60: cholesterol:dicetyl phosphate by the lipid …

  Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 1, 2014 · pp. 14–20 Read article →