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The Interaction of Extracellular Matrix and Growth FactorsBy Haile Nega Mulata, Gidey Gebremeskel
Abstract: The extracellular matrix (ECM) regulates cell behavior by influencing cell proliferation, survival, shape, migration and differentiation. ECM assembly is regulated by the 3D environment and the cellular tension that is transmitted through integrins. The hematopoietic microenvironment is a complex structure in which stem cells, progenitor cells, stromal cells, growth factors, and ECM molecules each interact to direct the coordinated regulation of blood cell development. Hematopoietic growth factors are any of …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 3, 2016 · pp. 9–23 Read article →