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    Serum Hepcidin Status of Sickle Cell Disease Subjects with Multiple Blood Transfusion in Nigeria

    Abstract: Objectives: No effective physiological mechanism for excess iron excretion is known in humans. Conditions such as sickle cell disease (SCD), where red blood cell transfusion is a frequently employed therapy can subsequently result in ready accumulation and circulation of exogenous iron as non-transferrin bound iron in tissues with possible impairment of iron homeostasis in them. Aim: The influence of multiple blood transfusions on the patterns of iron homeostasis in correlation …

    Published in Research and Reviews: A Journal of Medicine · Vol. 9, Issue 2, 2019 · pp. 1–9 Read article

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