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Formulation And Evaluation Of Captopril Sustained Release Tablet By Qbd Approach.By JAIMIN B. PATEL, DR. PARESH PRAJAPATI, DR. RAKSHIT SONALPAL, MR. BHAVIN BHIMANI, DR. UPENDRA PATEL
Abstract: The purpose of present study was to formulation and evaluation of Captopril sustained release tablet by QbD approach using size expanding polymer and cross linker. Captopril is a ACE inhibitor use in treatment of mild to moderate hypertension. Captopril having biological half-life of 2 hrs. The drugs gets degrade as its goes to higher pH, so we selected size expanding GRDDS. In formulation development study by using QbD, we found …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 1, 2023 · pp. 64–73 Read article →