3 publications
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Published Subscription Review Article
Assessing the Efficacy of Carica Papaya Leaf Extract in Preventing Thrombocytopenia: A ReviewBy Devendra S Mahale, Jagruti R. Girase, Deveshree Yashwantbhai Patel, Harsha Vasudev Chaudhari, Patil Divyashree Kantilal, Shraddha Pramod Amrutkar
Abstract: A clinical condition known as thrombocytopenia is characterized by a low platelet count (less than 150 × 103/μL) in the blood, which leads to an imbalance in hemostasis and can result in multiple deadly consequences. Although the exact causes are not always known, they always lead to death by interfering with the formation of platelets and encouraging their destruction. Research demonstrates that Carica papaya leaf has special medicinal and therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 25–33 Read article →
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Published Subscription Review Article
Exploring Chocolate’s Potential: A Review of Its Role in Drug Delivery and Health BenefitsBy Devendra S Mahale, Bhavika Rakesh Jaiswal, Apurva S. Patel, Pavan Somnath Gosavi, Prashant Bansilal Mahale, Neha R. Jaiswal
Abstract: The abstract explores the versatile nature of chocolate, highlighting its role as a medium for drug delivery systems due to its resistance to microbial growth and rich nutritional profile. Medicated chocolate, infused with drugs, offers a palatable solution to enhance patient compliance, particularly among children, while stimulating serotonin production for added therapeutic benefits. Cocoa, abundant in polyphenols, contributes to chocolate's health advantages, including cholesterol reduction and cardiovascular health. Scientific evidence …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 16–24 Read article →
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Published Subscription Original Research
A Comprehensive Exploration of Method Validation and Development in Pharmaceutical Analysis: Focus on Vortioxetine AnalysisBy Devendra S Mahale, Amit Kumar R. Dhankani, S.P. Pawar
Abstract: The pharmaceutical industry relies on rigorous method validation to ensure the accuracy, precision, and reliability of analytical techniques employed in drug testing and quality control. This comprehensive exploration delves into the validation parameters and guidelines essential for method validation, emphasizing accuracy, precision, linearity, detection and quantitation limits, specificity, range, robustness, and ruggedness. Validation plays a pivotal role in guaranteeing high-quality products, adhering to good manufacturing practices (GMP), and optimizing manufacturing …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 46–52 Read article →