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Biochemical and Biophysical Studies of the Dimerization Process of HIV-RNA GenomeBy Dr. Pratima Chaudhuri, Charu Thapliyal
Abstract: HIV infection is correlated with the dimerization of retroviral RNA genomes.Retroviruses are the only known group of viruses that contain two identical (or nearly identical) copies of the RNA genome within the virion. These RNA genomes are non-covalently joined together through a process known as genomic RNA dimerization. Uniquely, the RNA dimerization of the retroviral genome is of crucial importance for efficient retroviral replication. RNA dimerization is the non-covalent process …
Published in Research and Reviews: A Journal of Medicine · Vol. 1, Issue 2, 2011 · pp. 9–15 Read article →