2 publications

• Published Subscription 22 Feb 2019

  An Overview on Natural Polymers in Novel Drug Delivery System

  By Ayyappan T, S. Shanmugam, Vetrichelvan T

  Abstract: Any pharmaceutical formulation contains two ingredients, one is the active ingredient and other is an excipient. An excipients help in the manufacturing of dosage form and it also improve physicochemical parameters of the dosage form. Polymer plays an important role as excipients in any dosage form. They influence drug release and it should be compatible, nontoxic, stable, economic etc. They are broadly classified as natural polymers and synthetic polymer. They …

  Published in Trends in Drug Delivery · Vol. 3, Issue 2, 2016 · pp. 1–14 Read article →

• Published Subscription 22 Feb 2019

  UV Spectrophotometric Method for the Estimation of Etoposide and its Application in Study of Polymeric Nanoparticles

  By Ayyappan T, Shanmugam S, Vetrichelvan T

  Abstract: A rapid, economical, accurate and simple UV spectrophotometric method was developed for quantification of etoposide in bulk and pharmaceutical formulation and its application in the study of polymeric nanoparticles. The samples were quantified at 284 nm in both methanol and phosphate buffer saline (PBS) at pH 7.4. The method was linear (r2 > 0.99) over the range of 20–100 μg/ml, precise (RSD < 5%), accurate (recovery values close to 100%), …

  Published in Trends in Drug Delivery · Vol. 3, Issue 1, 2016 · pp. 46–51 Read article →