1 publication

• Published Subscription 14 Mar 2019

  QSAR Analysis on a Series of Triazole Based Tubulin Polymerization Inhibitors

  By Akanksha ., Vikas Mehta, Richa Dhingra, Neelima Dhingra

  Abstract: AbstractThe polymerization progression of microtubules is vital to their natural capacities. Polymerization flow allows microtubules to embrace spatial courses of action that can change quickly because of cell needs and, at times, to perform mechanical work. Compounds that interfere with the microtubule-tubulin equilibria in cells are helpful in the treatment of human diseases. A few triazoles mimics of combretastatin-benzothiazole (CAB) hybrids had good activity as inhibitors both of tubulin polymerization …

  Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 2, 2017 · pp. 5–20 Read article →