1 publication

• Published Subscription Review Article 30 Mar 2026

  Effect of Local Application of Phenytoin on Wound Healing in Surgical Wounds: A Scientific Review

  By Richa Jaiman, Bhavana Verma, Abhishek Pankaj

  Abstract: Surgical wound healing is a dynamic biological process influenced by local tissue response, vascularity, infection control, and systemic patient factors. Delayed wound healing contributes significantly to postoperative morbidity and healthcare costs. Phenytoin, a hydantoin derivative traditionally used as an antiepileptic agent, has demonstrated unexpected wound-healing properties when applied topically. This review critically evaluates experimental and clinical evidence regarding the role of locally applied phenytoin in enhancing wound healing in surgical …

  Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 1, 2026 · pp. 15–19 Read article →