structural vaccinology
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Vaccines Through Time: Conventional Foundations and Next-Gen Innovations–Part 1
Abstract: Vaccination serves as a critical pillar of global public health, markedly decreasing infection rates and associated mortality. Traditional vaccine platforms such as live attenuated, inactivated, toxoid, and subunit vaccines have demonstrated effectiveness against pathogens like Mycobacterium tuberculosis and Plasmodium spp., yet they are constrained by antigenic variability, limited immune persistence, and complex production processes. Breakthroughs in synthetic biology, structural antigen design, and computational vaccinology have driven the development of advanced …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 · pp. 53–70 Read article
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A Note on Vaccine Design Using Bioinformatics Methods and Applications
Abstract: Vaccines prevent infectious diseases caused by viruses and bacteria saving millions of lives.It consists of certain agents that resemble disease causative agentsand stimulates our immune system to recognize and fight foreign antigens. Immune function or an immune response is the fundamental basis of the vaccine's mechanism. Vaccines are pharmaceutical derivatives that provide an affordable way to prevent diseases.Various bioinformatics approaches can be incorporated into vaccine design studies and development. Reverse …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 1–9 Read article