redox rheostat
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The Redox Rheostat: A Review on Targeting the Oxidative Stress-to- Cell Death Continuum for Therapeutic Gain
Abstract: For a long time, oxidative stress was cast as a plain villain, something to be pushed down with antioxidants wherever it appeared. That view has changed. Reactive oxygen species (ROS) do real work in the cell. At low concentrations, molecules such as hydrogen peroxide act as signals. As stress increases, cells activate protective mechanisms to keep themselves safe. However, if the stress becomes too strong or lasts too long, these …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 Read article