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3 articles for “p16”
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Prognostic impact of individual and complex mutations of the k-ras, p16 and p53 genes on postoperative prognosis and overall survival of patients with gastric cancer
Abstract: Background: The aim of this study was to determine the post-operative overall survival and prognostic factors associated with k-ras, p16, p53 gene mutations in patients with gastric cancer.Materials: We used the paraffin-embedded specimens from 70 patients with gastric cancer who correspond with the investigation purpose (patients had performed D2 lymph node dissection, no pre and post-operation chemotherapy) from 2000 to 2015. The sample consisted of 49 (70.0%) males and 21 …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 9, Issue 1, 2022 · pp. 9–29 Read article
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Clinicopathological Study of Oral Malignant and Premalignant Lesions with p53 and p16 Immunostaining
Abstract: Oral cancer is a global problem, more in India. A study of 50 cases of oral lesions were conducted in a tertiary care hospital in Kolkata, India. Detailed clinical history was taken. Cytology, punch biopsy with histopathology and immunostaining with p53 and p16 were done in all the cases. A total of 31 cases (62.0%) were benign, 19 cases (38.0%) were malignant, with an age range of 26–69 years (mean …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 8, Issue 2, 2019 · pp. 20–24 Read article
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A Mini Review on Genes Associated with in vitro and in vivo Carbon Nanotubes Toxicity
Abstract: Carbon nanotubes (CNTs) are the most extensively used nanomaterials due to their unique properties and diverse applications. The potential toxicity caused due to the exposure of CNTs in vitro and in vivo is being widely studied. This mini review provides information about the genes responsible for inflammatory, fibrotic and apoptotic responses during single and multi-walled CNT toxicity. Based on published literature, the upregulated pro-inflammatory genes are EGR1, ATF3, FGF21, EGF1 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 1, 2019 · pp. 73–78 Read article