Search
2 articles for “Lung clone cell”
-
Biological Property of Lung Clone Cell Strain “Pyong-09-2”
Abstract: We cultivated lung clone cell strain, “Pyong-09-2” whose genetic characters are proper from fetal lung tissue-originated lung cell strain and found out their biological property. Lung clone cell strain, “Pyong-09-2” formed monolayer in which polygonic epithelioid cells are arranged uniformly, like original cell strain “Pyong-09-2” and their growth rate and activity are highest in medium containing 1% serum in 24～84 h of culture. Their viral infectious titer, plaque forming ability, …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 8, Issue 3, 2021 · pp. 29–34 Read article
-
Efficacy of Combination Therapy with Osimertinib and Afatinib in epidermal growth factor receptor-mutant non-small-cell lung cancer Patients
Abstract: Treatment options for patients with non-small-cell lung cancer who have epidermal growth factor receptor mutations are constrained by the emergence of resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Osimertinib or afatinib alone, when tested in a laboratory model, led to the formation of drug-resistant clones harboring epidermal growth factor receptor secondary mutations. However, combining these drugs prevented the emergence of such mutations. In a Phase II clinical trial, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 13–24 Read article