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125 articles for “path loss”
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In Silico Exploration of Podophyllum Hexandrum-Derived Phytocompounds as Potential Therapeutics Against Small Cell Lung Cancer (SCLC): A Molecular Docking Approach
Abstract: Small Cell Lung Cancer (SCLC) is a fast-growing and aggressive type of lung cancer that spreads quickly strongly associated with smoking. It is characterized by symptoms, such as persistent cough, breathing difficulties, or hoarseness, though it can sometimes be asymptomatic which makes early detection challenging. The tumor suppressor gene TP53 is critical in regulating the cell cycle and preventing uncontrolled cell division. Mutations in TP53 result in the loss of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 1–11 Read article
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Vertical Villages: Redefining Urban Living for a Sustainable Future
Abstract: As urbanization accelerates, cities face growing challenges in balancing population growth with sustainable resource use. Traditional horizontal sprawl is increasingly unsustainable, causing habitat loss, inefficient land use, and higher carbon emissions from long commutes and overstressed infrastructure. Addressing these issues, vertical villages offer an innovative, sustainable alternative for dense urban environments. Vertical villages are multi-story, integrated communities that combine residential, commercial, and communal spaces within compact areas. By optimizing land …
Published in International Journal of Architectural Design and Planning · Vol. 3, Issue 1, 2025 · pp. 7–17 Read article
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An Overview of Artificially Generated Neural Networks Inside the Brain’s Structure in an Alzheimer’s Disease Patient
Abstract: Alzheimer’s disease produces significant neuronal loss, while the precise mechanisms and timing are yet unknown. Other types of cell death, such necroptosis, parthanatosis, ferroptosis, and cuproptosis, need further investigation. Based on brain images of people with mild cognitive impairment, this study assesses artificial neural networks (ANNs) used to diagnose and predict Alzheimer’s disease (AD). This research was conducted considering growing recognition among researchers and medical professionals regarding the importance of …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 2, 2025 Read article
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A Promising Approach Towards Arthritis: Bacopa Monnieri
Abstract: Joint inflammation, pain, and a progressive loss of function are the hallmarks of arthritis, a chronic and crippling condition that frequently results in disability and a lower quality of life. The need for safer options is highlighted by the fact that while current therapy approaches, such as NSAIDs, corticosteroids, and disease-modifying antirheumatic medications, give symptomatic relief, they are usually linked to serious adverse effects. In this regard, the wellknown Ayurvedic …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 3, 2025 · pp. 76–91 Read article
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Secondary Metabolites in Drug Development: Tracing Their Historical and Therapeutic Impact
Abstract: Secondary metabolites, also known as natural products, exhibit a level of structural and chemical diversity unmatched by synthetic small molecule libraries. These compounds, which have evolved to possess drug-like properties, continue to be a primary source for new medications and drug leads. Their discovery has significantly impacted advancements in chemistry, biology, and medicine, influencing drug development and therapeutic strategies throughout history. Derived from primary metabolic pathways such as photosynthesis, glycolysis, …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 51–55 Read article