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23 articles for “Mutation Prediction”
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Uncovering the Elusive Threat: An Investigative Study on Polymorphic Viruses
Abstract: In the intricate landscape of cybersecurity, polymorphic viruses have prominently emerged, distinguishing themselves through their unique ability to continually modify their code, rendering them stealthy and challenging to detect. This comprehensive study embarks on a journey through the complex world of these viruses. It commences with a historical lens, meticulously tracing their roots, their initial manifestations, and the progressive sophistication of their code-altering techniques. The research then pivots to a …
Published in Journal Of Network security · Vol. 11, Issue 3, 2023 · pp. 10–21 Read article
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A Novel WPFM-Transformer Framework for DNA Sequence Classification using FASTA Data
Abstract: The identification of genetic variants, tracing of disease-associated mutations, and the reconstruction of evolutionary relationships from raw sequence data are all achieved by the analysis of DNA sequence. The FASTA format is plain text and is an easy-to-read format, which is why it has endured four decades of the field's growth into bioinformatics. Classical alignment programs like BLAST and Smith-Waterman work well with small data sets, but are limited by …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 2, 2026 Read article