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245 articles for “agent evaluation”
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Green Synthesis of Cobalt Oxide Nanoparticles Using Delonix regia Leaf
Abstract: Green synthesis of nanoparticles offers a sustainable and eco-friendly alternative to conventional methods. This study explores the biosynthesis of cobalt oxide nanoparticles (Co3O4 NPs) using Delonix regia leaf extract as a reducing and stabilizing agent. The synthesized Co3O4 NPs were characterized by UV-visible spectroscopy, Fourier transform infrared (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM), confirming their uniform spherical morphology with an average size of …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 1, 2025 · pp. 30–38 Read article
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Eco-Friendly Steel Making for a Sustainable Future
Abstract: The iron and steel industry is one of the most energy-intensive sectors, accounting for approximately 5% of global energy consumption and contributing around 7% of worldwide CO2 emissions. The industry's carbon footprint is particularly challenging to reduce, as carbon plays a crucial role as a stoichiometric reducing agent in conventional steel production. The reduction of iron ore during the manufacture of primary (virgin) steel is responsible for a sizable amount …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 15, Issue 3, 2025 · pp. 6–31 Read article
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Histological Effects of the Antibiotic Gentamicin on the Ovarian Tissue of Female White Laboratory Rats
Abstract: This study aimed to evaluate the histological alterations induced by Gentamicin in the ovarian tissue of white laboratory rats. A total of 12 adult female rats were used and randomly divided into two groups, with each group consisting of six animals. The experimental group received Gentamicin at a dose of 120 mg/kg body weight administered as an injection once daily, while the control group received an equivalent volume of normal …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 1–8 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article