Research and Reviews: A Journal of Neuroscience Original Research

Deep Learning-Based Alzheimer’s Disease Detection: A CNN Approach

  1. Malik Hyder Ali Department Computer Science and Engineering Akal University
  2. Harsh Kumar Department of Computer Science and Engineering

Abstract

Alzheimer’s disease (AD) is a neurological condition that worsens with time and impairs a patient’s quality of life by causing cognitive loss. For prompt intervention and management of AD, early identification is essential. In this work, we propose a deep learning-based method for automatically classifying Alzheimer’s disease from medical imaging data using convolutional neural networks (CNNs). Our algorithm is intended to evaluate brain MRI images and detect anatomical variations suggestive of AD. The CNN architecture is designed to discriminate between people who are healthy, those who have mild cognitive impairment, and people who have Alzheimer’s disease with high accuracy and robustness. The model demonstrated noteworthy performance in terms of accuracy, sensitivity, and specificity when it was trained on a dataset of MRI scans. According to our findings, CNN-based models present a viable means of diagnosing Alzheimer’s disease early and precisely, which can help doctors decide on the best course of treatment. This work demonstrates the promise of deep learning for neuroimaging and its use in diagnosing neurodegenerative diseases.

Keywords

References (11)

  1. Finder VH. Alzheimer's Disease: A General Introduction and Pathomechanism. Journal of Alzheimer's Disease. 2010;22(s3):S5-S19. doi:10.3233/jad-2010-100975
  2. Ji H, Liu Z, Yan WQ, Klette R. Early Diagnosis of Alzheimer's Disease Using Deep Learning. Proceedings of the 2nd International Conference on Control and Computer Vision. 2019:87-91. doi:10.1145/3341016.3341024
  3. Aruchamy S, Haridasan A, Verma A, Bhattacharjee P, Nandy SN, Ram Krishna Vadali S. Alzheimer’s Disease Detection using Machine Learning Techniques in 3D MR Images. 2020 National Conference on Emerging Trends on Sustainable Technology and Engineering Applications (NCETSTEA). 2020:1-4. doi:10.1109/ncetstea48365.2020.9119923
  4. Fong JX, Shapiai MI, Tiew YY, Batool U, Fauzi H. Bypassing MRI Pre-processing in Alzheimer's Disease Diagnosis using Deep Learning Detection Network. 2020 16th IEEE International Colloquium on Signal Processing & Its Applications (CSPA). 2020:219-224. doi:10.1109/cspa48992.2020.9068680
  5. Helaly HA, Badawy M, Haikal AY. Deep Learning Approach for Early Detection of Alzheimer’s Disease. Cognitive Computation. 2021;14(5):1711-1727. doi:10.1007/s12559-021-09946-2
  6. Al Shehri W. Alzheimer’s disease diagnosis and classification using deep learning techniques. PeerJ Computer Science. 2022;8:e1177. doi:10.7717/peerj-cs.1177
  7. Hussain E, Hasan M, Hassan SZ, Hassan Azmi T, Rahman MA, Zavid Parvez M. Deep Learning Based Binary Classification for Alzheimer’s Disease Detection using Brain MRI Images. 2020 15th IEEE Conference on Industrial Electronics and Applications (ICIEA). 2020:1115-1120. doi:10.1109/iciea48937.2020.9248213
  8. Kaur U, Kumar H, Kaur R. AI in Healthcare. Advances in Systems Analysis, Software Engineering, and High Performance Computing. 2024:140-169. doi:10.4018/979-8-3693-3609-0.ch006
  9. A A, M P, Hamdi M, Bourouis S, Rastislav K, Mohmed F. Evaluation of Neuro Images for the Diagnosis of Alzheimer's Disease Using Deep Learning Neural Network. Frontiers in Public Health. 2022;10. doi:10.3389/fpubh.2022.834032
  10. Murugan S, Venkatesan C, Sumithra MG, Gao XZ, Elakkiya B, Akila M, et al. DEMNET: A Deep Learning Model for Early Diagnosis of Alzheimer Diseases and Dementia From MR Images. IEEE Access. 2021;9:90319-90329. doi:10.1109/access.2021.3090474
  11. Puente-Castro A, Fernandez-Blanco E, Pazos A, Munteanu CR. Automatic assessment of Alzheimer’s disease diagnosis based on deep learning techniques. Computers in Biology and Medicine. 2020;120:103764. doi:10.1016/j.compbiomed.2020.103764
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