Volume 1, Issue 2 (2014)
Published
Table of contents
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Synthesis and Electrochemical Study of 1-[2′, 4′-dinitrophenyl)-3, 5-dimethyl-4- [4′′-(substituted)sulphonamoylphenyl] Azopyrazoles
Abstract: Electrochemical behavior of 1-(2',4'-dinitrophenyl)-3,5-dimethyl-4-[4"-(substituted) sulphonamoylphenyl] azopyrazole (DDSPA) was studied in Britton-Robinson (BR) buffer range of pH 3.5–12 at dropping mercury electrode (DME) and glassy carbon electrode (GCE). Cathodic differential pulse polarographic peak is obtained at DME in the pH range 3.5–12. Cyclic voltammogram exhibited a well-defined, irreversible cathodic and anodic peak at GCE. At pH 3.5–12, the reduction peak exhibited a tendency to split into two peaks. The first 8e- …
Published in Trends in Drug Delivery · Vol. 1, Issue 2, 2014 · pp. 1–7 Read article
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Regenerative Endodontics: Nano 3D scaffolds as Dental Materials and Stem Cells for Dental Tissue Regeneration
Abstract: In dentistry, for maintaining any tissue in a healthy state, focus is on prevention, treatment and repair of the diseased tissue. Current treatments for diseases of tooth structures rely on the use of classical endodontic procedures which in some cases are limited success rate. The use of stem cells in regenerative therapies have been shown to have promising applications in various debilitating diseases like neurodegenerative disease, diabetes, cancer and dental …
Published in Trends in Drug Delivery · Vol. 1, Issue 2, 2014 · pp. 14–23 Read article
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Intrapocket Drug Delivery System: A Spatial Tool for Periodontitis
Abstract: Periodontitis is a disease attributable to multiple infectious agents. It results from extension of the inflammatory process initiated in the gingiva to the supporting periodontal tissues. Periodontal pockets provide natural reservoir bathed by gingival crevicular fluid that is easily accessible for the insertion of a delivery device. Intra-pocket, sustained release systems have emerged as a novel paradigm for the future research. Controlled release delivery of antimicrobials is a therapeutic intervention …
Published in Trends in Drug Delivery · Vol. 1, Issue 2, 2014 · pp. 24–29 Read article
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Formulation and Evaluation of Transdermal Drug Delivery of Piroxicam
Abstract: The aim of the present study was to formulate transdermal films loaded with Piroxicam (PX). Transdermal films were prepared by using sodium alginate (SA) and xanthan gum (XG) as biopolymers by varying the blend ratios viz., 10:0, 8:2, 6:4, 4:6 and 2:8 (w/w %) through solution casting method. The drug loaded membranes were evaluated for thickness, tensile behaviours, and content uniformity. In-vitro diffusion was determined by Franz diffusion cell. Piroxicam …
Published in Trends in Drug Delivery · Vol. 1, Issue 2, 2014 · pp. 8–13 Read article