Research and Reviews: Journal of Oncology and Hematology
Volume 13, Issue 1 (2024)
Table of contents
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An Insight into Childhood Malignancy
Abstract: Childhood cancers represent a significant public health concern, affecting a vulnerable population with unique biological and developmental characteristics. The aim of this article is to describe the main causes and different types of malignancies in childhood. By understanding the contributing factors towards malignancy in childhood one can plan for the preventive measures and early diagnosis and treatment modalities can be adopted. Even though the treatment patterns have improved, people are …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 07–12 Read article
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A Case Report of Advanced Periampullary Carcinoma: Palliative Chemotherapy Following Whipple’s Surgery
Abstract: This case report delves into the complex management of a 60-year-old female patient diagnosed with Stage 4 periampullary carcinoma, encompassing the pancreatic head. Presenting with difficulty in eating, diagnostic investigations, including ERCP, confirmed the diagnosis, leading to Whipple's surgery. Postoperatively, liver metastasis was identified, prompting palliative intervention through stenting and the initiation of a GEMOX chemotherapy regimen. The patient responded favorably to the initial chemotherapy cycle, leading to a planned …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 1–6 Read article
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Efficacy of Combination Therapy with Osimertinib and Afatinib in epidermal growth factor receptor-mutant non-small-cell lung cancer Patients
Abstract: Treatment options for patients with non-small-cell lung cancer who have epidermal growth factor receptor mutations are constrained by the emergence of resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Osimertinib or afatinib alone, when tested in a laboratory model, led to the formation of drug-resistant clones harboring epidermal growth factor receptor secondary mutations. However, combining these drugs prevented the emergence of such mutations. In a Phase II clinical trial, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 13–24 Read article
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Recent Development Technique in Management of Cancer
Abstract: Cancer develops when a change in one's genetic makeup leads to the development of tumour cells. These clusters of malignant cells eventually develop into tumours. Tumours can shed cancerous cells, which can then travel through the lymphatic system or the circulatory system to other organs. In the medical field, this occurrence is referred to as metastasis. Cancer cells proliferate even when they have no instructions to do so. Despite the …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 25–41 Read article
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Analyzing Failures and Challenges in Oncology: Integration of Artificial Intelligence in Healthcare
Abstract: The present study focused on investigating the challenges and failures that had been embarked during the deployment of artificial intelligence technologies within the field of oncology in healthcare. Through precise research and statistical analysis, we aimed to elucidate the specific circumstances surrounding each failure, providing insights into the root causes, consequences, and subsequent developments. The present study was aimed to offer a detailed understanding of the challenges faced through artificial …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 42–50 Read article