Research and Reviews : A Journal of Life Sciences
Volume 14, Issue 2 (2024)
Table of contents
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A Perspective Review on Role of Environmental Pollutants in Developing Neurodegenerative Diseases
Abstract: As human society progresses towards industrialization, an excess number of environmental pollutants are released to our ecosystem, which significantly contribute in causing various health issues primarily associated with neurodegenerative diseases such as cognitive disorder, dementia, anxiety, Alzheimer, Parkinson etc. Because of their high global occurrence, these diseases have attracted attention in recent decades, however, the etiology of these diseases remains unclear. Pollutants are discharged into the environment by natural events …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 1–18 Read article
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Enzyme Stability Prediction using BERT and CNN-A Deep Learning Approach for Enhanced Biocatalysis
Abstract: An important factor in determining the efficacy of industrial enzymes used in various biotechnological applications is their stability. The goal of this study is to develop a predictive model for industrial enzyme stability, which is essential to the efficiency of these enzymes in biotechnological applications. The research takes a comprehensive strategy to comprehend the parameters affecting enzyme stability by combining statistical analysis, deep learning algorithms (BERT and CNN), and molecular …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 19–35 Read article
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Revolutionizing Healthcare Environments: Exploring Innovative Furniture Design for Hospitals
Abstract: The healthcare landscape is continuously evolving, demanding innovative solutions to address the diverse needs of patients, caregivers, and medical staff. The design of hospital furniture plays a pivotal role in patient comfort, recovery, and overall experience. This dissertation explores the realm of new furniture design for hospitals, exploring a myriad of concepts and considerations aimed at revolutionizing healthcare environments. Furthermore, the research investigates the need for high-quality, ergonomic, and aesthetically …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 36–48 Read article
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A Study to Find the Relation Between School Bag Weight and Musculoskeletal Discomfort in School Going Children
Abstract: Background: School bags are one of the several forms of manual load carriage used by school children. Carrying school bags that exceed 10% of body weight can lead to heightened energy expenditure, causing increased forward lean of the neck and trunk, reduced lung capacity, and elevated cardio-respiratory measures. Musculoskeletal disorders (MSDs) are characterized by injuries or disorders affecting muscles, tendons, ligaments, cartilage, or spinal discs, as diagnosed by healthcare providers, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 49–58 Read article
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Non -Invasive Ways to Detect Cancer
Abstract: Cancer is a diverse group of diseases characterized by uncontrolled cell growth and division, affecting millions worldwide and being a leading cause of death. The disease typically involves genetic alterations that disrupt the normal balance of cell growth, leading to the formation of tumors. Tumors can be benign, posing no threat as they do not spread, or malignant, capable of invading nearby tissues and metastasizing. There are more than 100 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 59–67 Read article
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ISGylation: A Key Host Cellular Defense Mechanism
Abstract: ISGylation, a crucial process of the innate immune response, has garnered increasing attention for its involvement in host's defense against pathogenic infections as well in cancer progression. The key player of ISGylation, ISG15, is stimulated by type I interferons (IFNs). ISG15 covalently binds with viral (influenza NS1A and nucleoproteins) and host (Nedd4, filamin B and CHMP5) target proteins and this interaction inhibits the viral replication process and release of viral …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 2, 2024 · pp. 68–80 Read article