Research & Reviews: A Journal of Drug Design & Discovery
Volume 2, Issue 1 (2015)
Published
Table of contents
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Synthesis of Some Novel Formazan Derivatives with Potential Antimicrobial Spectrum
Abstract: A sequence of new substituted formazan derivatives has been synthesized from corresponding aryl diazonium chloride and Schiff base in pyridine. The synthesized compounds were recognized by spectral studies and screened for the antimicrobial activities for those drugs. Keywords: Schiff Base, Formazan, Antimicrobial ActivityCite this Article:Jain A, Radiya P. Synthesis of Some Novel Formazan Derivatives with Potential Antimicrobial Spectrum. Research & Reviews: A Journal of Drug Design & Discovery. 2015; 2(1): …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 1, 2015 · pp. 1–5 Read article
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Pharmaceutical Vistas of Swarna Kalpa: An Overview
Abstract: Swarna (gold) has substantial therapeutic value, which has been indicated in different classics of Ayurveda as well as in contemporary science. To achieve these therapeutic indications, Swarna is converted in to suitable dosage form like Bhasma, Parpati, Kupipakwa, Pottali, Vasant Kalpa, Lauha Kalpa, Vati etc. There are approximately 150 Swarna Yogas in different dosage forms in classical literature of Ayurveda. The above mentioned dosage forms are prepared by unique pharmaceutical …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 1, 2015 · pp. 13–18 Read article
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Spectrophotometric Method for the Estimation of Levosulpiride in Bulk Drug and Formulations
Abstract: Levosulpiride having D2-dopamine receptor antagonistic activity gives ant depressive and antiulcer effect. There are three new simple accurate, rapid, economical and precise procedures for spectrophotometric estimation of Levosulpiride in bulk and pharmaceutical formulation. Levosulpiride was estimated at 291.5 nm in 0.1 N NaOH, 290 nm in 0.1 N HCl and 292.5 nm in 6.8 phosphate buffer. Linearity range was found to be 10–50 µg/mL in all the three methods. The …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 1, 2015 · pp. 19–23 Read article
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In Silico Tau Protein Kinase I Inhibitory Activity of Some Commercially Available Flavonoids
Abstract: Molecular docking is a frequently used tool in computer-aided structure-based rational drug design. Flavonoids are a group of natural products which exhibits various biological and pharmacological activities. The primary objective of this study was to investigate the tau protein kinase I inhibitory activity of flavonoids using in silico docking studies. Memantine, a known neuro-receptor antagonist is currently used in the treatment of Alzheimer’s disease (AD). In silico docking studies were …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 1, 2015 · pp. 6–12 Read article