Research and Reviews : Journal of Computational Biology
Volume 11, Issue 2 (2022)
Published
Table of contents
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In Silico Drug Designing of Breast Cancer in Homo sapiens
Abstract: Breast cancer is a severe health concern in India, with the highest mortality rate among women. It is brought on by uncontrolled cell division and has the potential to spread to other body regions. As a transcription factor, interactions with estrogen receptor (ER) alpha are primarily responsible for malignant tumors through regulating the transcription of numerous genes. Because most of the medications now used to treat breast cancer have significant …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 2, 2022 · pp. 12–27 Read article
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IoT-based Smart Transportation System for Passenger Comfort
Abstract: Industry 4.0 now includes a far wider range of topics, including smart transportation management, smart cities, and smart healthcare. It is important to emphasise that among Industry 4.0’s main objectives are innovation, the adoption of new business models, and the development of new revenue sources. Vehicle tracking data is vital in intelligent transportation systems (ITS) for both drivers and passengers who want to understand where they are to cross or …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 2, 2022 · pp. 28–35 Read article
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Tools and Techniques for Whole-Genome Alignments
Abstract: The prediction of evolutionary relationships between two or more genomes at the nucleotide level is known as whole-genome alignment (WGA). It possesses characteristics of both gene orthology prediction and collinear sequence alignment. WGAs are useful for genome-wide analyses like phylogenetic inference, genome annotation, and function prediction. So many solutions have been developed despite the fact that this problem is difficult. This article provides an overview of the approaches used to …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 2, 2022 · pp. 36–38 Read article
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An Overview of Bioinformatics
Abstract: What is bioinformatics? Biology and computer science? How are they related to each other? This question, I believe, could have been raised even in the nineteenth century, when computer and biological technologies were just emerging. The great Louis Pasteur (1822–1895) was researching the relationship between the presence of a particular microorganism and alcohol fermentation in a particular French city. Ada Lovelace, a mathematician who shared Charles Babbage’s vision, was attempting …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 2, 2022 · pp. 8–11 Read article