Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, No. 2 (2026)

Gut-Brain Axis and Classical Ayurveda: Journal of AYUSH 15(2)

By STM Journals ·

This issue of the Journal of AYUSH, which covers India's traditional medicine systems, sets classical Ayurvedic and Unani ideas beside modern physiology. Papers look at the gut-brain axis, the intestine as the seat of Vata, a Unani account of brain disorders, and an exploratory study of a classical urine test in people already diagnosed with diabetes. Two single-patient case reports describe Ayurvedic management of knee osteoarthritis and of a skin condition diagnosed as pemphigus vulgaris. Case reports describe individual patients and cannot show that a treatment works.

What's in this issue

  1. Interrelationship Between Psychological Stress and Gastrointestinal Physiology: Role of the Gut–Brain Axis

    Shweta Mali, Tanvi P. Desai

    Stress and digestion are closely linked. This paper examines the gut-brain axis: how stress hormones, gut-brain signalling and psychosocial factors can disturb motility, secretion and the gut microbiota, and how that relates to conditions such as irritable bowel syndrome.

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  2. Ashaya as Abode: Reconciling Ayurvedic Vata Theory with Intestinal Neurophysiology

    Gameti Mansviben, Kalpana Raje, Syamlal S, Dharmendra Mishra, K. Arul Prasadh

    Ayurveda describes ashayas, the internal sites where substances reside, and names the pakwashaya (the large-intestine region) as the principal seat of Vata dosha. This paper tries to reconcile that classical idea with modern intestinal neurophysiology.

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  3. Unani Concepts of Brain Pathology: Humoral Mechanisms in Māddī Neurological Disorders

    Shagufta Parveen, Patel Mohd Furqan Ahmad, Usmani Sana Kamal, Sana Kauser Ateeque Ahmed

    How did classical Unani physicians explain brain disease? This paper reviews Su'-i-Mizaj Maddi Dimagh, brain disorders attributed to the accumulation of morbid matter, through the Unani ideas of mizaj (temperament) and akhlat (humours).

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  4. Assessing Taila Bindu Pariksha as a Diagnostic and Prognostic test for Diabetes Mellitus

    Saumya Dwivedi, Avadhesh Kumar

    Taila Bindu Pariksha is a classical Ayurvedic urine test in which a drop of oil is placed on the sample. In 60 patients with known diabetes, the authors compared oil-drop patterns between controlled and uncontrolled cases; the test has not been validated against standard blood-glucose testing.

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  5. Clinical Efficacy of Laxadi Taila Janubasti in the Management of Janusandhigata Vata (Knee Osteoarthritis): A Case Report

    Madhavi Seetha

    A single-patient case report on Janubasti, a localised oil-retention therapy used for degenerative knee disorders, applied here with Laxadi Taila to a patient with Janusandhigata Vata, the Ayurvedic condition that resembles knee osteoarthritis. The authors note that controlled clinical studies are needed to establish whether it is effective.

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  6. A Clinical Case Study of Kaphaja Visarpa W.S.R to Pemphigus Vulgaris

    Nihal N. Kanziya

    A single-patient case study of a 58-year-old woman with type 2 diabetes and skin lesions diagnosed as pemphigus vulgaris, read through the Ayurvedic framework of Kaphaja Visarpa, a classical rapidly spreading skin condition. One case does not show that the approach works and is not a substitute for medical care.

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