International Journal of Molecular Biotechnological Research
Volume 2, Issue 1 (2024)
Table of contents
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Gene Annotation of Cancer Vaccine for Homo sapiens
Abstract: Objectives: Gene annotation helps us to deduce the structural and functional aspects of a gene that encodes for a functional protein in our body. Thus, by determining the coding sequence and gene location we can derive meaningful insights as to what these genes do in our body. In this study, an unknown gene, cancer vaccine for Homo sapiens has been studied and annotated. Methods: This study was based on a …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 1–14 Read article
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Multitarget Molecular Docking Using Curcuma longa Phytocompounds for Polycystic Ovary Syndrome Treatment
Abstract: Objective: The primary goal of this research is to understand and describe specific aspects of molecular interaction, it includes studying various aspects such as binding affinity, binding mode, and stability of the ligand-protein complex. Molecular docking is a computational technique used to predict the preferred orientation of one molecule to a second when bound together to form a stable complex. In this study, molecular docking will be employed to stimulate …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 15–28 Read article
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Integrating Network Pharmacology and Molecular Docking to Investigate Boerhavia diffusa for Pancreatic Cancer Treatment
Abstract: Objective: In this study, network pharmacology was applied to determine the therapeutic effects of the bioactive compounds of Boerhavia diffusa. Network pharmacology can unearth the underlying mechanisms between drugs and the disease targets and aids in the discovery of novel medications for complex conditions such as cancer. Methods: To predict the molecular mechanisms of action of Boerhavia diffusa in the treatment of was screened using the GeneCards database. The Venn …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 29–49 Read article
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Deciphering the Pathophysiology of Migraine: Understanding Trigeminovascular System Activity and the Importance of the Gut-Brain Axis
Abstract: Migraine, a prevalent and disabling neurological condition, manifests in distinct phases: premonitory, aura, headache, postdrome, and interictal. Being a primary contributor to adult disability, it presents a substantial economic challenge on a global scale. Even with extensive research spanning centuries, the complete grasp of its root causes continues to evade us. This intricate neurovascular disorder primarily involves local vasodilation of intracranial and extracerebral blood vessels, coupled with simultaneous stimulation of …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 50–61 Read article
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Evolution and Impact of Forensic DNA Typing in Modern Investigation
Abstract: Forensic DNA typing is sometimes called DNA fingerprinting. Immigration, paternity, and criminal investigations use forensic DNA typing. Forensic genetics today includes bodily fluid identification, fast DNA analysis, forensic microbiology, and phenotypic profiling. Human cells contain DNA, a molecular code. Human DNA sequences are 99.9% the same in everyone. Every person has almost 0.1% unique DNA. Forensic experts also worry about this 0.1 percent of DNA that is unique. There are …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 1, 2024 · pp. 62–66 Read article