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• Published Subscription 1 Mar 2019

  Development and Characterization of Mucoadhesive Microspheres Containing a Model Antidiabetic Drug

  By Mudit Dixit, R. Narayana Charyulu, Sompalli Prashanthi, Nisha G. Shetty

  Abstract: The present work was envisaged to reduce the dosing frequency and improve patient compliance by designing and evaluating sustained release mucoadhesive (SRM) microspheres of metformin hydrochloride (MH) for an effective control of diabetes type-2. Microspheres were prepared by emulsification solvent evaporation method using sodium alginate, carbopol 934P (CP), and sodium carboxy methyl cellulose (SCMC) as a mucoadhesive polymers. The microspheres exhibits good mucoadhesive properties and showed high drug entrapment efficiency. …

  Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 2, 2015 · pp. 12–19 Read article →