2 publications
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Published Subscription
Methodologies for in silico and in vitro Test of Biphenylalanine Compounds as Potential HIV-1 gp120 Attachment InhibitorsBy SK. Md. Jakaria Al-Mujahidy
Abstract: We postulate that biphenylalanine and its derivatives are propitious candidates to inhibit the binding of HIV-gp120 to CD4 T-cell. Many biphenylalanine derivatives are synthesized chemically and also prevailing in nature. We have proposed atom- and bond-based 2D TOMOCOMD-CARDD approach to identify the best derivative. Moreover, according to our proposition, the principal law simulated from in silico interaction of gp120 with CD4 can be tested by ELISA in vitro. Furthermore, the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 2, Issue 3, 2015 · pp. 38–42 Read article →
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Published Subscription
Potentiality of Bacteriocins as the Attachment Inhibitors of HIV-1 gp120By SK. Md. Jakaria Al-Mujahidy
Abstract: It is postulated that some bacteriocin derivatives are consummate candidates to inhibit the binding of HIV gp120 to CD4 T-cell. From the discovery of bacteriocin compounds in 1925 and forth, nearly 300 bacteriocins have been identified. Of various bacteriocins, there are some which have been used successfully for inhibiting both animal and human pathogens. Unfortunately, no large extent research has been found in the development of various bacteriocins as HIV …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 5, Issue 3, 2015 · pp. 18–23 Read article →