2 publications

• Published Subscription 26 Mar 2019

  Molecular Docking: A Powerful Approach for Structure based Drug Discovery

  By Shipra Senger, Tulika Verma

  Abstract: Molecular Docking is a method which predicts the preferred orientation of one molecule to a second when bound to each other to form a stable complex. Knowledge of the preferred orientation in turn may be used to predict the strength of association or binding affinity between two molecules using, for example, scoring functions. The associations between biologically relevant molecules such as proteins, nucleic acids, carbohydrates, and lipids play a central …

  Published in Research & Reviews: A Journal of Bioinformatics · Vol. 3, Issue 2, 2016 · pp. 15–19 Read article →

• Published Subscription 4 Mar 2019

  Recent Trends in Drug Repositioning for Discovery of New Anticancer Drugs

  By Shipra Senger

  Abstract: Drug repositioning, the process of finding new uses of existing drugs, has been gaining popularity in recent years. The availability of several established clinical drug libraries and rapid advances in disease biology, genomics and bioinformatics has accelerated the pace of both activity-based and in silico drug repositioning. Drug repositioning has attracted particular attention from the communities engaged in anticancer drug discovery due to the combination of great demand for new …

  Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 3, Issue 2, 2016 · pp. 35–38 Read article →