2 publications

• Published Subscription Review Article 23 Mar 2026

  Cellular Mechanisms of Autophagy in Carcinogenesis: A Narrative Review

  By Sharique Ahmad, Shekhar Srivastava, Raushan Kumar, Pooja Srivastav, Pushpendra D. Pratap, Faiza Hasan Khan

  Abstract: Autophagy is a highly conserved lysosomal degradation pathway essential for cellular homeostasis, metabolic adaptation, and survival under stress. In the context of carcinogenesis, autophagy exhibits a paradoxical and stage-dependent role. During early tumor development, autophagy acts as a tumor-suppressive mechanism by limiting genomic instability, oxidative stress, and chronic inflammation. Conversely, in established malignancies, cancer cells exploit autophagy to sustain growth, survive hostile tumor microenvironments, and resist anticancer therapies. Increasing evidence …

  Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 23–28 Read article →

• Published Subscription Review Article 23 Mar 2026

  Advances in Simulation and Surgical Skill Training Evolution: Narrative Integrative Review

  By Shekhar Srivastava, Shahid Hassan, Rokib Hasan Morad, Swati Srivastava, Siddhartha Chandel, Sharique Ahmad

  Abstract: Simulation-based education has emerged as a cornerstone of contemporary general surgery training, driven by increasing emphasis on patient safety, competency-based education, and rapid technological innovation. Traditional apprenticeship models, while foundational, are constrained by reduced operative exposure, work-hour limitations, and variability in clinical case mix. In this context, simulation provides a structured, reproducible, and safe environment for acquisition, assessment, and refinement of surgical skills across the training continuum. This narrative review …

  Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 1, 2026 · pp. 7–13 Read article →