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Shashikant Verma

Affiliation: Department of Chemistry, Nari Shiksha Niketan PG College, Mona Chandrawati Gupta Marg, Kaiserbagh, Lucknow
Department: Research Scholar
Location: India

1 article

Published Subscription Original Research 3 May 2025
Exploring Antimalarial Activity of Chalcone Derivatives through QSAR
By Neerja Shukla, Anita Singh, Rahila Khan, Shashikant Verma, Anushka Shukla, Kumari Suman, Bechan Sharma

Abstract: Background: The core structure of chalcones contains a reactive α,β-unsaturated system within the aromatic rings, which plays a key role in mediating various biological effects. These effects include enzyme inhibition, anticancer activity, anti-inflammatory properties, as well as antibacterial, antifungal, antimalarial, antiprotozoal, and anti-filarial actions.Modifying the structure by introducing substituent groups to the aromatic ring can enhance potency, reduce toxicity, and expand their range of pharmacological actions. Methods: A total of …

Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 1–6 Read article