1 publication

• Published Subscription Review Article 14 Jun 2026

  pH-Triggered In-Situ Nasal Gel Systems for Migraine Therapy: A Review

  By Siya Vijaykumar Chawhan, Sayali Manoj Sayare, Rukmini Sankar Girhepunje, Tilottama Moreshwar Gatkine

  Abstract: Intranasal drug delivery has gained considerable attention as a non-invasive route for delivering drugs to both systemic circulation and the central nervous system, particularly for the treatment of migraine. Traditional nasal formulations such as sprays and drops often show poor therapeutic performance due to rapid mucociliary clearance and limited retention within the nasal cavity. To overcome these challenges, in-situ gel systems have been designed, which transform from a liquid to …

  Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article →